Endocrine Abstracts

Background: Subclinical hypothyroidism is associated with a number of cardiovascular risk factors such as hypertension, hypercholesterolemia, and diastolic dysfunction, but only limited data exist on long-term outcome of levothyroxine substitution therapy.Objectives: To examine effects of levothyroxine substitution treatment on mortality in patients with subclinical hypothyroidism.Study design: Historical cohort study.<p class=...

Introduction: Subclinical hypothyroidism (SCH) is a common condition and can lead to impaired systolic and diastolic cardiac function. However, controversy remains over the potential benefits of levothyroxine substitution in patients with SCH and concomitant heart disease. We aimed to examine the effects of levothyroxine treatment on all-cause mortality in patients diagnosed with SCH and heart disease.Methods: Primary care patients aged 18 years and olde...